Corrigendum: Isolation and characterization of a bacteriophage phiEap-2 infecting multidrug resistant Enterobacter aerogenes

نویسندگان

  • Erna Li
  • Xiao Wei
  • Yanyan Ma
  • Zhe Yin
  • Huan Li
  • Weishi Lin
  • Xuesong Wang
  • Chao Li
  • Zhiqiang Shen
  • Ruixiang Zhao
  • Huiying Yang
  • Aimin Jiang
  • Wenhui Yang
  • Jing Yuan
  • Xiangna Zhao
چکیده

Enterobacter aerogenes (Enterobacteriaceae) is an important opportunistic pathogen that causes hospital-acquired pneumonia, bacteremia, and urinary tract infections. Recently, multidrug-resistant E. aerogenes have been a public health problem. To develop an effective antimicrobial agent, bacteriophage phiEap-2 was isolated from sewage and its genome was sequenced because of its ability to lyse the multidrug-resistant clinical E. aerogenes strain 3-SP. Morphological observations suggested that the phage belongs to the Siphoviridae family. Comparative genome analysis revealed that phage phiEap-2 is related to the Salmonella phage FSL SP-031 (KC139518). All of the structural gene products (except capsid protein) encoded by phiEap-2 had orthologous gene products in FSL SP-031 and Serratia phage Eta (KC460990). Here, we report the complete genome sequence of phiEap-2 and major findings from the genomic analysis. Knowledge of this phage might be helpful for developing therapeutic strategies against E. aerogenes.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2016